Motif ID: ELK1,4_GABP{A,B1}.p3

Z-value: 3.905


Transcription factors associated with ELK1,4_GABP{A,B1}.p3:

Gene SymbolEntrez IDGene Name
ELK1 2002 ELK1, member of ETS oncogene family
ELK4 2005 ELK4, ETS-domain protein (SRF accessory protein 1)
GABPA 2551 GA binding protein transcription factor, alpha subunit 60kDa
GABPB1 2553 GA binding protein transcription factor, beta subunit 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GABPB1chr15_-_484348960.802.0e-04Click!
GABPAchr21_+_260291280.562.5e-02Click!
ELK4chr1_-_203868622-0.312.4e-01Click!
ELK1chrX_-_47394937-0.155.7e-01Click!


Activity profile for motif ELK1,4_GABP{A,B1}.p3.

activity profile for motif ELK1,4_GABP{A,B1}.p3


Sorted Z-values histogram for motif ELK1,4_GABP{A,B1}.p3

Sorted Z-values for motif ELK1,4_GABP{A,B1}.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of ELK1,4_GABP{A,B1}.p3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_109729176 4.545 NM_023016
ANKRD57
ankyrin repeat domain 57
chr2_+_176842368 4.446 NM_006554
MTX2
metaxin 2
chr3_+_180348818 4.319 NM_006218
PIK3CA
phosphoinositide-3-kinase, catalytic, alpha polypeptide
chr2_+_27659396 3.990 NM_032434
ZNF512
zinc finger protein 512
chr2_+_64605049 3.660 AFTPH
aftiphilin
chr7_+_107997527 3.597 DNAJB9
DnaJ (Hsp40) homolog, subfamily B, member 9
chr7_+_107997544 3.563 NM_012328
DNAJB9
DnaJ (Hsp40) homolog, subfamily B, member 9
chr9_+_113433364 3.441 NM_001015882
NM_004125
DNAJC25
DNAJC25-GNG10
DnaJ (Hsp40) homolog, subfamily C , member 25
DNAJC25-GNG10 readthrough
chr2_+_64604940 3.367 NM_001002243
NM_017657
NM_203437
AFTPH


aftiphilin


chr7_-_107997132 3.268 NM_182529
NM_001130475
THAP5

THAP domain containing 5

chr7_+_107171809 2.900 CBLL1
Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1
chr1_+_36169260 2.765 NM_024852
NM_177422
EIF2C3

eukaryotic translation initiation factor 2C, 3

chr9_+_114288899 2.763 NM_133465
KIAA1958
KIAA1958
chr20_+_56659693 2.762 NM_001001433
NM_001134772
NM_001134773
NM_003763
STX16



syntaxin 16



chr3_+_133861894 2.734 UBA5
ubiquitin-like modifier activating enzyme 5
chr2_+_74007495 2.709 DGUOK
deoxyguanosine kinase
chr9_+_114289178 2.668 KIAA1958
KIAA1958
chr2_+_74007523 2.658 DGUOK
deoxyguanosine kinase
chr2_+_74007439 2.638 NM_080916
NM_080918
DGUOK

deoxyguanosine kinase

chr5_+_72830029 2.532 BTF3
basic transcription factor 3
chr20_+_33750645 2.516 NM_080748
ROMO1
reactive oxygen species modulator 1
chr4_+_119825983 2.473 NM_020961
METTL14
methyltransferase like 14
chr2_-_109728693 2.464 SEPT10
septin 10
chr20_-_33750457 2.421 NM_001198989
NM_021100
NFS1

NFS1 nitrogen fixation 1 homolog (S. cerevisiae)

chr2_-_109728958 2.400 NM_144710
NM_178584
SEPT10

septin 10

chr20_+_60395515 2.386 NM_001024
RPS21
ribosomal protein S21
chr5_+_36912656 2.385 NIPBL
Nipped-B homolog (Drosophila)
chr14_+_75688042 2.363 C14orf118
chromosome 14 open reading frame 118
chr7_+_86619805 2.328 NM_021145
DMTF1
cyclin D binding myb-like transcription factor 1
chr5_+_72830003 2.322 NM_001037637
NM_001207
BTF3

basic transcription factor 3

chr13_+_30089829 2.307 NM_005800
USPL1
ubiquitin specific peptidase like 1
chr20_-_49008445 2.243 NM_003859
DPM1
dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
chr3_+_133861820 2.238 NM_024818
UBA5
ubiquitin-like modifier activating enzyme 5
chr13_-_30089509 2.230 HMGB1
high-mobility group box 1
chr1_+_181708068 2.223 NM_001174061
NM_173156
NM_201568
NM_201569
SMG7



Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)



chr1_+_181708235 2.214 SMG7
Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)
chr14_+_75688025 2.194 C14orf118
chromosome 14 open reading frame 118
chr14_+_75687997 2.181 NM_017926
NM_017972
C14orf118

chromosome 14 open reading frame 118

chr10_-_43212681 2.179 HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr15_+_21361901 2.162 MKRN3
makorin ring finger protein 3
chr2_+_187162969 2.147 NM_001145000
NM_002210
ITGAV

integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)

chr10_+_97879645 2.142 ZNF518A
zinc finger protein 518A
chr14_+_34521945 2.140 SRP54
signal recognition particle 54kDa
chr2_+_69974581 2.137 NM_006857
SNRNP27
small nuclear ribonucleoprotein 27kDa (U4/U6.U5)
chr1_+_212520899 2.108 NM_020197
SMYD2
SET and MYND domain containing 2
chr6_+_169844213 2.089 C6orf120
chromosome 6 open reading frame 120
chr6_+_169844161 2.085 NM_001029863
C6orf120
chromosome 6 open reading frame 120
chr22_+_20350272 2.084 NM_014337
NM_148175
NM_148176
PPIL2


peptidylprolyl isomerase (cyclophilin)-like 2


chr6_+_169844186 2.083 C6orf120
chromosome 6 open reading frame 120
chr2_+_118288724 2.079 NM_006773
DDX18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr3_+_9379706 2.070 NM_001114092
NM_015453
THUMPD3

THUMP domain containing 3

chr20_+_49008754 2.059 NM_014484
MOCS3
molybdenum cofactor synthesis 3
chr2_+_118288754 2.058 DDX18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr3_+_52296893 2.054 GLYCTK
glycerate kinase
chr5_+_36912595 2.054 NM_015384
NM_133433
NIPBL

Nipped-B homolog (Drosophila)

chr16_+_21926939 2.052 NM_001164579
C16orf52
chromosome 16 open reading frame 52
chr2_+_118562499 2.033 NM_016133
INSIG2
insulin induced gene 2
chr2_+_118288753 2.028 DDX18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr2_-_74915722 2.026


chr7_+_86619580 2.024 NM_001142326
NM_001142327
DMTF1

cyclin D binding myb-like transcription factor 1

chr2_+_32244406 2.020 NM_001193513
NM_001193514
NM_001193515
NM_017964
SLC30A6



solute carrier family 30 (zinc transporter), member 6



chr9_-_32991518 2.012 NM_001195249
NM_001195254
NM_001195248
NM_001195250
NM_001195251
NM_001195252
NM_175069
NM_175073
APTX







aprataxin







chr7_+_6583560 2.004 NM_001134387
NM_001134388
NM_001134389
NM_018106
ZDHHC4



zinc finger, DHHC-type containing 4



chr10_-_18988172 2.002


chr3_+_52296875 1.978 NM_001144951
NM_145262
GLYCTK

glycerate kinase

chr20_+_48560327 1.976 PTPN1
protein tyrosine phosphatase, non-receptor type 1
chr2_+_239000395 1.973 ASB1
ankyrin repeat and SOCS box containing 1
chr5_-_36912487 1.973 LOC646719
hypothetical LOC646719
chr20_+_42947754 1.970 NM_003404
NM_139323
YWHAB

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide

chr20_+_48560326 1.959 PTPN1
protein tyrosine phosphatase, non-receptor type 1
chr2_+_46779827 1.953 NM_144949
SOCS5
suppressor of cytokine signaling 5
chr6_-_7334940 1.952 NM_001170692
NM_001170693
NM_205864
CAGE1


cancer antigen 1


chr16_+_68353738 1.933 NM_007014
NM_199423
WWP2

WW domain containing E3 ubiquitin protein ligase 2

chr1_-_118273701 1.929 GDAP2
ganglioside induced differentiation associated protein 2
chr20_+_60395623 1.919 RPS21
ribosomal protein S21
chr15_+_56850681 1.907 NM_001040450
NM_001040453
FAM63B

family with sequence similarity 63, member B

chr20_+_48560315 1.906 PTPN1
protein tyrosine phosphatase, non-receptor type 1
chr1_-_52272020 1.902 NM_138417
KTI12
KTI12 homolog, chromatin associated (S. cerevisiae)
chr3_-_15443985 1.899 NM_152396
METTL6
methyltransferase like 6
chr14_+_34521854 1.885 NM_001146282
NM_003136
SRP54

signal recognition particle 54kDa

chr15_+_56850776 1.884 FAM63B
family with sequence similarity 63, member B
chr11_+_43337042 1.883 TTC17
tetratricopeptide repeat domain 17
chr6_-_169844023 1.877 NM_182552
WDR27
WD repeat domain 27
chr6_+_169844128 1.877 C6orf120
chromosome 6 open reading frame 120
chr5_+_138705416 1.871 NM_016480
PAIP2
poly(A) binding protein interacting protein 2
chr2_+_187163232 1.865 ITGAV
integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
chr20_+_48560264 1.862 NM_002827
PTPN1
protein tyrosine phosphatase, non-receptor type 1
chr20_+_42947764 1.854 YWHAB
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
chr4_+_110956085 1.853 NM_018983
NM_032993
GAR1

GAR1 ribonucleoprotein homolog (yeast)

chr12_+_68150332 1.843 NM_001042555
NM_006654
FRS2

fibroblast growth factor receptor substrate 2

chr7_-_30600868 1.835 LOC285949
hypothetical protein LOC285949
chr20_+_16658608 1.817 NM_003092
NM_198220
SNRPB2

small nuclear ribonucleoprotein polypeptide B

chr1_-_181708022 1.815 LOC284649
hypothetical LOC284649
chr7_+_39572396 1.812 NM_020192
C7orf36
chromosome 7 open reading frame 36
chr20_+_43028533 1.808 NM_006282
STK4
serine/threonine kinase 4
chr8_+_11179724 1.797 MTMR9
myotubularin related protein 9
chr6_+_160068553 1.790 WTAP
Wilms tumor 1 associated protein
chr5_+_148705169 1.787 NM_152407
GRPEL2
GrpE-like 2, mitochondrial (E. coli)
chr5_+_69732561 1.784 SMA4
glucuronidase, beta pseudogene
chr1_+_118273887 1.781 NM_006784
WDR3
WD repeat domain 3
chr7_+_99451110 1.780 NM_003439
ZKSCAN1
zinc finger with KRAB and SCAN domains 1
chr6_+_160068544 1.769 WTAP
Wilms tumor 1 associated protein
chr6_+_160068531 1.761 WTAP
Wilms tumor 1 associated protein
chr20_+_43028590 1.760 STK4
serine/threonine kinase 4
chr11_-_117628211 1.756 NM_198275
MPZL3
myelin protein zero-like 3
chr21_+_36614347 1.755 NM_015358
MORC3
MORC family CW-type zinc finger 3
chr1_+_196392513 1.751 NM_133494
NEK7
NIMA (never in mitosis gene a)-related kinase 7
chr16_+_55777739 1.750 NM_133368
RSPRY1
ring finger and SPRY domain containing 1
chr5_+_138705445 1.744 PAIP2
poly(A) binding protein interacting protein 2
chr17_+_42355482 1.743 NM_001012511
NM_004287
NM_054022
GOSR2


golgi SNAP receptor complex member 2


chr1_+_93584088 1.740 DR1
down-regulator of transcription 1, TBP-binding (negative cofactor 2)
chr5_+_147743734 1.735 NM_030793
NM_205836
FBXO38

F-box protein 38

chr1_+_52380633 1.732 NM_004799
NM_007323
NM_007324
ZFYVE9


zinc finger, FYVE domain containing 9


chr2_+_65308332 1.723 NM_001005386
NM_005722
ACTR2

ARP2 actin-related protein 2 homolog (yeast)

chr7_+_107171514 1.721 NM_024814
CBLL1
Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1
chr2_+_218790143 1.721 ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr4_-_101086891 1.719 NM_001031723
DNAJB14
DnaJ (Hsp40) homolog, subfamily B, member 14
chr5_+_65258316 1.712 ERBB2IP
erbb2 interacting protein
chr2_+_3362449 1.709 NM_016030
TTC15
tetratricopeptide repeat domain 15
chr6_+_170457774 1.709 FAM120B
family with sequence similarity 120B
chr1_+_93584078 1.706 DR1
down-regulator of transcription 1, TBP-binding (negative cofactor 2)
chr15_-_81216179 1.706


chr10_-_43212703 1.704 NM_001098207
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr1_+_93584051 1.703 DR1
down-regulator of transcription 1, TBP-binding (negative cofactor 2)
chr14_+_68935172 1.703 SLC39A9
solute carrier family 39 (zinc transporter), member 9
chr6_+_160068598 1.703 NM_152857
WTAP
Wilms tumor 1 associated protein
chr2_+_46779553 1.700 NM_014011
SOCS5
suppressor of cytokine signaling 5
chr16_+_82399132 1.695 HSBP1
heat shock factor binding protein 1
chr6_+_7535404 1.693 NM_152551
SNRNP48
small nuclear ribonucleoprotein 48kDa (U11/U12)
chr10_+_18988282 1.690 NM_178815
ARL5B
ADP-ribosylation factor-like 5B
chr16_+_82399073 1.688 NM_001537
HSBP1
heat shock factor binding protein 1
chr13_+_44937025 1.685 NM_031431
COG3
component of oligomeric golgi complex 3
chr11_+_10729357 1.677 NM_014633
CTR9
Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr1_+_118273869 1.676 WDR3
WD repeat domain 3
chr5_-_74098641 1.668 NM_032380
NM_170681
NM_170691
GFM2


G elongation factor, mitochondrial 2


chr1_+_93584064 1.668 NM_001938
DR1
down-regulator of transcription 1, TBP-binding (negative cofactor 2)
chr3_-_133861182 1.661 NM_032169
ACAD11
acyl-CoA dehydrogenase family, member 11
chr1_-_93583910 1.660 LOC100131564
hypothetical LOC100131564
chr17_+_42355492 1.658 GOSR2
golgi SNAP receptor complex member 2
chr3_+_102763369 1.656 NM_017819
RG9MTD1
RNA (guanine-9-) methyltransferase domain containing 1
chr4_+_109761170 1.653 NM_000995
NM_033625
RPL34

ribosomal protein L34

chr2_+_48395271 1.647 NM_002158
FOXN2
forkhead box N2
chr7_+_30600926 1.637 GARS
glycyl-tRNA synthetase
chr14_+_89792646 1.637 NM_002802
PSMC1
proteasome (prosome, macropain) 26S subunit, ATPase, 1
chr2_+_128565222 1.634 NM_020120
UGGT1
UDP-glucose glycoprotein glucosyltransferase 1
chr2_+_239000306 1.632 NM_001040445
ASB1
ankyrin repeat and SOCS box containing 1
chr15_+_63948823 1.624 NM_004663
RAB11A
RAB11A, member RAS oncogene family
chr20_+_42537927 1.623 NM_001039199
NM_024331
TTPAL

tocopherol (alpha) transfer protein-like

chr14_+_68935133 1.621 NM_018375
SLC39A9
solute carrier family 39 (zinc transporter), member 9
chr7_+_27746335 1.614 TAX1BP1
Tax1 (human T-cell leukemia virus type I) binding protein 1
chr10_-_43212166 1.611 NM_001098208
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr4_-_101086754 1.607 DNAJB14
DnaJ (Hsp40) homolog, subfamily B, member 14
chr2_+_218790109 1.606 NM_152862
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr20_+_48560354 1.600 PTPN1
protein tyrosine phosphatase, non-receptor type 1
chr12_+_49080858 1.594 NM_001170803
NM_001170804
NM_001170808
NM_052879
NM_199188
NM_199190
LARP4





La ribonucleoprotein domain family, member 4





chr16_+_68353662 1.593 WWP2
WW domain containing E3 ubiquitin protein ligase 2
chr5_+_147743753 1.591 FBXO38
F-box protein 38
chr6_+_4721640 1.587 NM_004824
CDYL
chromodomain protein, Y-like
chr2_-_65308220 1.583 LOC729324
hCG1986447
chr13_+_78953495 1.577 NDFIP2
Nedd4 family interacting protein 2
chr11_+_8660913 1.573 RPL27A
ribosomal protein L27a
chr1_+_22224571 1.571 HSPC157
hypothetical LOC29092
chr2_+_178685396 1.571 NM_152945
RBM45
RNA binding motif protein 45
chr3_+_15444056 1.559 NM_033083
EAF1
ELL associated factor 1
chr16_+_8799170 1.553 NM_000303
PMM2
phosphomannomutase 2
chr6_+_170705345 1.546 NM_001172085
NM_003194
TBP

TATA box binding protein

chr13_+_25726755 1.526 NM_001260
CDK8
cyclin-dependent kinase 8
chr16_+_29994797 1.523 PPP4C
protein phosphatase 4, catalytic subunit
chr5_+_138705469 1.521 PAIP2
poly(A) binding protein interacting protein 2
chr4_+_79916576 1.521 BMP2K
BMP2 inducible kinase
chr22_+_39817733 1.520 EP300
E1A binding protein p300
chr15_+_41450568 1.520 NM_014444
TUBGCP4
tubulin, gamma complex associated protein 4
chr12_+_99185289 1.514 SCYL2
SCY1-like 2 (S. cerevisiae)
chr6_+_126349327 1.500 TRMT11
tRNA methyltransferase 11 homolog (S. cerevisiae)
chr12_+_99184977 1.498 SCYL2
SCY1-like 2 (S. cerevisiae)
chr20_+_19945930 1.494 NM_016100
NM_181528
NAA20

N(alpha)-acetyltransferase 20, NatB catalytic subunit

chr11_+_123997968 1.492 TBRG1
transforming growth factor beta regulator 1
chr14_+_68934855 1.478 SLC39A9
solute carrier family 39 (zinc transporter), member 9
chr3_+_133861425 1.473 UBA5
ubiquitin-like modifier activating enzyme 5
chr11_+_123997983 1.470 TBRG1
transforming growth factor beta regulator 1
chr20_+_60246982 1.468 OSBPL2
oxysterol binding protein-like 2
chr18_+_31963851 1.457 ELP2
elongation protein 2 homolog (S. cerevisiae)
chr16_+_29994818 1.456 PPP4C
protein phosphatase 4, catalytic subunit
chr13_+_37821964 1.454 UFM1
ubiquitin-fold modifier 1
chr10_-_51293220 1.448 NM_006327
TIMM23
TIMM23B
translocase of inner mitochondrial membrane 23 homolog (yeast)
translocase of inner mitochondrial membrane 23 homolog B (yeast)
chr11_-_6459139 1.447 NM_012402
ARFIP2
ADP-ribosylation factor interacting protein 2
chr5_+_110455768 1.443 NM_139281
WDR36
WD repeat domain 36
chr16_+_24648446 1.439 NM_014494
TNRC6A
trinucleotide repeat containing 6A
chr14_+_56805358 1.439 NM_018229
MUDENG
MU-2/AP1M2 domain containing, death-inducing
chr20_+_60246972 1.438 NM_014835
NM_144498
OSBPL2

oxysterol binding protein-like 2

chr4_+_110956360 1.434 GAR1
GAR1 ribonucleoprotein homolog (yeast)
chr20_-_5041482 1.430 NM_001009923
NM_001009924
NM_001009925
NM_014145
C20orf30



chromosome 20 open reading frame 30



chr18_+_31963879 1.425 NM_018255
ELP2
elongation protein 2 homolog (S. cerevisiae)
chr11_+_123997980 1.424 TBRG1
transforming growth factor beta regulator 1
chr16_-_8798973 1.415 NM_015421
TMEM186
transmembrane protein 186
chr6_+_7335011 1.413 NM_031480
RIOK1
RIO kinase 1 (yeast)
chr17_+_70520339 1.410 NM_001545
ICT1
immature colon carcinoma transcript 1
chr6_+_126349268 1.409 NM_001031712
TRMT11
tRNA methyltransferase 11 homolog (S. cerevisiae)
chr7_-_16651885 1.409 NM_020319
ANKMY2
ankyrin repeat and MYND domain containing 2
chr12_+_99185334 1.408 NM_017988
SCYL2
SCY1-like 2 (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.38 1.94e-39 GO:0044260 cellular macromolecule metabolic process
1.31 8.89e-30 GO:0043170 macromolecule metabolic process
1.25 2.22e-28 GO:0044237 cellular metabolic process
1.39 1.15e-21 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.44 3.97e-21 GO:0090304 nucleic acid metabolic process
1.47 1.18e-19 GO:0010467 gene expression
1.19 2.17e-19 GO:0008152 metabolic process
1.39 5.12e-19 GO:0044267 cellular protein metabolic process
1.20 5.18e-18 GO:0044238 primary metabolic process
1.47 5.98e-18 GO:0016070 RNA metabolic process
1.30 1.55e-14 GO:0034641 cellular nitrogen compound metabolic process
1.42 4.09e-14 GO:0009059 macromolecule biosynthetic process
1.43 5.38e-14 GO:0034645 cellular macromolecule biosynthetic process
1.32 9.54e-14 GO:0071841 cellular component organization or biogenesis at cellular level
1.28 6.21e-13 GO:0006807 nitrogen compound metabolic process
1.76 6.39e-13 GO:0016071 mRNA metabolic process
1.68 1.73e-12 GO:0006396 RNA processing
1.31 3.38e-12 GO:0071842 cellular component organization at cellular level
1.26 3.65e-12 GO:0071840 cellular component organization or biogenesis
1.84 8.36e-12 GO:0016032 viral reproduction
1.85 3.46e-11 GO:0006397 mRNA processing
1.27 3.66e-11 GO:0019538 protein metabolic process
1.09 6.54e-11 GO:0009987 cellular process
1.57 8.95e-11 GO:0046907 intracellular transport
1.38 1.38e-10 GO:0006996 organelle organization
1.64 1.96e-10 GO:0009057 macromolecule catabolic process
1.25 2.02e-10 GO:0016043 cellular component organization
1.90 1.27e-09 GO:0008380 RNA splicing
1.51 1.39e-09 GO:0045184 establishment of protein localization
1.67 1.67e-09 GO:0044265 cellular macromolecule catabolic process
1.52 1.73e-09 GO:0015031 protein transport
2.08 4.50e-09 GO:0000375 RNA splicing, via transesterification reactions
1.28 1.05e-08 GO:0044249 cellular biosynthetic process
1.44 1.47e-08 GO:0008104 protein localization
1.27 1.98e-08 GO:0009058 biosynthetic process
2.06 2.13e-08 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.06 2.13e-08 GO:0000398 nuclear mRNA splicing, via spliceosome
1.75 1.03e-07 GO:0030163 protein catabolic process
1.75 4.30e-07 GO:0044257 cellular protein catabolic process
1.21 4.43e-07 GO:0060255 regulation of macromolecule metabolic process
1.75 5.50e-07 GO:0051603 proteolysis involved in cellular protein catabolic process
1.59 9.23e-07 GO:0006974 response to DNA damage stimulus
1.76 1.14e-06 GO:0006412 translation
1.75 1.27e-06 GO:0006511 ubiquitin-dependent protein catabolic process
1.35 1.84e-06 GO:0033036 macromolecule localization
1.29 2.20e-06 GO:0006464 protein modification process
1.73 2.22e-06 GO:0019941 modification-dependent protein catabolic process
1.78 2.64e-06 GO:0032446 protein modification by small protein conjugation
1.37 2.66e-06 GO:0044248 cellular catabolic process
1.71 2.95e-06 GO:0070647 protein modification by small protein conjugation or removal
1.72 3.45e-06 GO:0043632 modification-dependent macromolecule catabolic process
1.39 5.12e-06 GO:0007049 cell cycle
1.23 7.18e-06 GO:0010468 regulation of gene expression
1.55 7.85e-06 GO:0070727 cellular macromolecule localization
1.55 8.95e-06 GO:0034613 cellular protein localization
1.27 9.41e-06 GO:0043412 macromolecule modification
1.63 9.58e-06 GO:0006886 intracellular protein transport
1.78 1.24e-05 GO:0016567 protein ubiquitination
1.31 1.53e-05 GO:0009056 catabolic process
1.42 2.12e-05 GO:0033554 cellular response to stress
1.50 3.24e-05 GO:0000278 mitotic cell cycle
1.33 3.28e-05 GO:0051641 cellular localization
1.17 4.99e-05 GO:0019222 regulation of metabolic process
1.37 5.58e-05 GO:0032774 RNA biosynthetic process
1.40 9.24e-05 GO:0022402 cell cycle process
2.02 9.33e-05 GO:0048193 Golgi vesicle transport
1.34 9.77e-05 GO:0051649 establishment of localization in cell
1.44 1.12e-04 GO:0022403 cell cycle phase
1.70 1.15e-04 GO:0010608 posttranscriptional regulation of gene expression
2.38 1.28e-04 GO:0006353 transcription termination, DNA-dependent
1.42 1.34e-04 GO:0016192 vesicle-mediated transport
1.61 1.80e-04 GO:0051301 cell division
1.17 1.91e-04 GO:0031323 regulation of cellular metabolic process
1.76 5.48e-04 GO:0033365 protein localization to organelle
1.21 6.90e-04 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.76 6.98e-04 GO:0071843 cellular component biogenesis at cellular level
1.16 6.98e-04 GO:0080090 regulation of primary metabolic process
1.42 1.18e-03 GO:0051726 regulation of cell cycle
2.31 1.70e-03 GO:0072594 establishment of protein localization to organelle
1.75 1.80e-03 GO:0022613 ribonucleoprotein complex biogenesis
1.47 1.81e-03 GO:0034621 cellular macromolecular complex subunit organization
1.35 2.69e-03 GO:0043933 macromolecular complex subunit organization
1.19 2.93e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.59 2.95e-03 GO:0048285 organelle fission
1.29 3.16e-03 GO:0044085 cellular component biogenesis
1.81 3.24e-03 GO:0006417 regulation of translation
1.33 5.26e-03 GO:0008219 cell death
2.60 6.57e-03 GO:0006369 termination of RNA polymerase II transcription
1.79 6.68e-03 GO:0010498 proteasomal protein catabolic process
1.79 6.68e-03 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
1.68 7.06e-03 GO:0000075 cell cycle checkpoint
1.33 7.80e-03 GO:0016265 death
1.66 8.20e-03 GO:0071156 regulation of cell cycle arrest
2.15 8.32e-03 GO:0031123 RNA 3'-end processing
1.40 9.32e-03 GO:0006259 DNA metabolic process
2.08 1.62e-02 GO:0022618 ribonucleoprotein complex assembly
1.55 1.70e-02 GO:0000087 M phase of mitotic cell cycle
1.67 1.77e-02 GO:0006457 protein folding
1.17 1.86e-02 GO:0031326 regulation of cellular biosynthetic process
1.31 2.08e-02 GO:0006351 transcription, DNA-dependent
1.50 2.24e-02 GO:0010564 regulation of cell cycle process
1.38 2.36e-02 GO:0071822 protein complex subunit organization
1.17 2.40e-02 GO:0009889 regulation of biosynthetic process
1.65 2.63e-02 GO:0006605 protein targeting
1.34 2.67e-02 GO:0006915 apoptosis
1.62 2.80e-02 GO:0048011 nerve growth factor receptor signaling pathway
2.01 2.92e-02 GO:0071826 ribonucleoprotein complex subunit organization
1.54 2.94e-02 GO:0000280 nuclear division
1.54 2.94e-02 GO:0007067 mitosis
1.34 3.19e-02 GO:0012501 programmed cell death
1.43 3.40e-02 GO:0016044 cellular membrane organization
1.73 3.44e-02 GO:0022415 viral reproductive process
1.92 3.74e-02 GO:0006414 translational elongation
1.43 3.80e-02 GO:0000279 M phase
1.42 4.39e-02 GO:0061024 membrane organization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.17 1.17e-56 GO:0005622 intracellular
1.18 1.53e-56 GO:0044424 intracellular part
1.23 5.94e-48 GO:0043231 intracellular membrane-bounded organelle
1.23 1.73e-47 GO:0043227 membrane-bounded organelle
1.20 2.07e-45 GO:0043229 intracellular organelle
1.20 1.30e-44 GO:0043226 organelle
1.30 4.02e-35 GO:0005634 nucleus
1.26 3.29e-27 GO:0044446 intracellular organelle part
1.25 6.99e-26 GO:0044422 organelle part
1.18 1.09e-24 GO:0005737 cytoplasm
1.45 1.22e-23 GO:0044428 nuclear part
1.41 2.91e-21 GO:0031974 membrane-enclosed lumen
1.41 8.91e-21 GO:0070013 intracellular organelle lumen
1.40 3.05e-20 GO:0043233 organelle lumen
1.45 5.56e-19 GO:0031981 nuclear lumen
1.20 1.90e-17 GO:0044444 cytoplasmic part
1.82 4.49e-16 GO:0030529 ribonucleoprotein complex
1.26 9.25e-14 GO:0032991 macromolecular complex
1.43 3.15e-12 GO:0005654 nucleoplasm
1.25 1.83e-09 GO:0043228 non-membrane-bounded organelle
1.25 1.83e-09 GO:0043232 intracellular non-membrane-bounded organelle
1.30 2.90e-09 GO:0005829 cytosol
2.25 7.85e-09 GO:0005681 spliceosomal complex
1.04 5.06e-06 GO:0005623 cell
1.04 6.63e-06 GO:0044464 cell part
1.52 8.59e-06 GO:0005730 nucleolus
1.23 1.40e-05 GO:0031090 organelle membrane
2.35 1.47e-05 GO:0071013 catalytic step 2 spliceosome
1.19 3.68e-05 GO:0043234 protein complex
1.40 6.79e-05 GO:0044451 nucleoplasm part
1.28 1.43e-04 GO:0005739 mitochondrion
1.37 4.83e-04 GO:0031967 organelle envelope
1.74 6.16e-04 GO:0005840 ribosome
1.66 7.79e-04 GO:0016604 nuclear body
1.91 8.29e-04 GO:0016607 nuclear speck
1.35 1.73e-03 GO:0031975 envelope
1.60 2.58e-03 GO:0005635 nuclear envelope
1.75 3.72e-03 GO:0044445 cytosolic part
1.37 9.01e-03 GO:0005694 chromosome
1.73 1.06e-02 GO:0031965 nuclear membrane
2.03 1.31e-02 GO:0016591 DNA-directed RNA polymerase II, holoenzyme
1.34 2.23e-02 GO:0044431 Golgi apparatus part
2.61 2.48e-02 GO:0030532 small nuclear ribonucleoprotein complex
1.37 2.73e-02 GO:0000139 Golgi membrane
1.20 2.78e-02 GO:0012505 endomembrane system
1.91 4.06e-02 GO:0000790 nuclear chromatin
1.87 4.34e-02 GO:0042470 melanosome
1.87 4.34e-02 GO:0048770 pigment granule

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.19 3.98e-21 GO:0005515 protein binding
1.10 7.79e-18 GO:0005488 binding
1.30 5.29e-17 GO:0003676 nucleic acid binding
1.60 6.33e-14 GO:0003723 RNA binding
1.23 8.11e-06 GO:0000166 nucleotide binding
1.24 1.30e-05 GO:0008270 zinc ion binding
1.25 2.50e-05 GO:0035639 purine ribonucleoside triphosphate binding
1.24 3.57e-05 GO:0017076 purine nucleotide binding
1.24 6.14e-05 GO:0032553 ribonucleotide binding
1.24 6.14e-05 GO:0032555 purine ribonucleotide binding
1.82 2.62e-04 GO:0008168 methyltransferase activity
1.25 5.47e-04 GO:0005524 ATP binding
1.24 7.58e-04 GO:0030554 adenyl nucleotide binding
1.25 7.91e-04 GO:0032559 adenyl ribonucleotide binding
1.12 8.41e-04 GO:0003824 catalytic activity
1.77 8.89e-04 GO:0016741 transferase activity, transferring one-carbon groups
1.66 1.72e-03 GO:0003713 transcription coactivator activity
1.18 3.71e-03 GO:0003677 DNA binding
1.77 5.30e-03 GO:0003735 structural constituent of ribosome
1.18 5.66e-03 GO:0046914 transition metal ion binding
1.32 7.97e-03 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.90 8.29e-03 GO:0008026 ATP-dependent helicase activity
1.90 8.29e-03 GO:0070035 purine NTP-dependent helicase activity
1.31 1.05e-02 GO:0016817 hydrolase activity, acting on acid anhydrides
1.45 1.09e-02 GO:0003712 transcription cofactor activity
1.45 1.25e-02 GO:0000988 protein binding transcription factor activity
1.45 1.25e-02 GO:0000989 transcription factor binding transcription factor activity
1.31 1.31e-02 GO:0016462 pyrophosphatase activity
1.97 1.48e-02 GO:0008565 protein transporter activity
1.30 2.32e-02 GO:0017111 nucleoside-triphosphatase activity
1.51 3.79e-02 GO:0016881 acid-amino acid ligase activity
1.19 4.39e-02 GO:0016740 transferase activity
1.94 4.83e-02 GO:0008135 translation factor activity, nucleic acid binding